Science AMA Series: We’re researchers at the NNF Center for Basic Metabolic Research, University of Copenhagen. We recently published a study showing that obesity may be inherited through epigenetic modifications in sperm. Ask us anything!

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Hello Reddit!

We are Ida Donkin, Soetkin Versteyhe, Lars R. Ingerslev, and Romain Barrès from the Novo Nordisk Foundation Center for Basic Metabolic Research.

We recently published a study that shows that sperm from obese men carry a distinct epigenetic signature compared to lean men, in particular at genes controlling brain development and function. In addition, we also looked at gastric bypass patients before and after surgery, and found that the sperm methylome is remodeled notably at gene regions implicated in the central control of appetite.

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Links: The actual paper: http://ift.tt/1QioyP6

NY Times http://ift.tt/1IrBXU7 The Guardian http://ift.tt/1lyHJIT

Our research group: http://ift.tt/1IPGfEJ

">Science AMA Series: We’re researchers at the NNF Center for Basic Metabolic Research, University of Copenhagen. We recently published a study showing that obesity may be inherited through epigenetic modifications in sperm. Ask us anything!