A protein called ApoE4 worsens the brain damage caused by tangles of another protein associated with Alzheimer’s disease, research shows. In the absence of ApoE, tau tangles did very little harm to brain cells. The findings suggest a possible therapeutic target for the disease.

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A protein called ApoE4 worsens the brain damage caused by tangles of another protein associated with Alzheimer’s disease, research shows. In the absence of ApoE, tau tangles did very little harm to brain cells. The findings suggest a possible therapeutic target for the disease.