See the source article by following the link below: Cancer is fundamentally a disease of the genome, caused by alterations such as DNA mutations that cause cells to grow out of control and form tumors. By sequencing the cancer genome and studying the changes associated with cancer, we can begin to identify molecular subtypes of cancer and develop new cancer therapies that target specific genomic lesions. The Cancer Genome Atlas (TCGA) began in 2005 to map the key genomic changes in cancer and has comprehensively characterized 33 types of cancer including 10 rare cancers, and produced a data set of over 2 petabytes for access by the research community. This feat could not have been accomplished without large-scale collaboration with scientists and institutions across the United States and Canada. TCGA will be wrapping up this year, but I look forward to continuing this work through the NCI’s Center for Cancer Genomics with many new projects that will take TCGA’s initial exploratory work a step further. Our current and ongoing projects integrate genomic data with clinical data, such as treatments and outcomes, to better understand the link between genomics and patient care, and how we can apply genomics to improving clinical oncology. Ask Me Anything about how team science works and about cancer genomics, past, present, and future! Also you can learn more about TCGA here: http://ift.tt/H1CI5O About CCG here http://ift.tt/1NGelaz and our new programs here: http://ift.tt/1poh43g I’ll be back for a bit at 11 am EST (8 am PST, 4 pm UTC) and again later at 2:30 pm EST (11:30 am PST, 7:30 pm UTC) to answer your questions, ask me anything! ">Science AMA Series: Headline: I’m Jean Claude Zenklusen, director of The Cancer Genome Atlas (TCGA), a landmark project of the National Cancer Institute and NHGRI to map genomic changes in cancer. I’m here to talk anything and everything big data, team science, and cancer genomics. AMA!
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