Researchers found that inhibiting cholesterol esterification can potentiate the antitumor activity of CD8+ T cells (also known as killer T cells). This new way of improving T-cell function might be used as a complement to current cancer immunotherapies, such as immune checkpoint blockade.

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Researchers found that inhibiting cholesterol esterification can potentiate the antitumor activity of CD8+ T cells (also known as killer T cells). This new way of improving T-cell function might be used as a complement to current cancer immunotherapies, such as immune checkpoint blockade.