In 2010, OxyContin was reformulated to deter misuse of the drug. As a result, opioid mortality declined. But heroin mortality increased, as OxyContin abusers switched to heroin. There was no reduction in combined heroin/opioid mortality: each prevented opioid death was replaced with a heroin death.

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In 2010, OxyContin was reformulated to deter misuse of the drug. As a result, opioid mortality declined. But heroin mortality increased, as OxyContin abusers switched to heroin. There was no reduction in combined heroin/opioid mortality: each prevented opioid death was replaced with a heroin death.