Sequencing 50,000+ human exomes, and pairing the data with electronic health records reveals that participants had on average 21 alleles with loss of function mutations, and ~3.5% of participants had mutations that were likely to be clinically relevant.

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Sequencing 50,000+ human exomes, and pairing the data with electronic health records reveals that participants had on average 21 alleles with loss of function mutations, and ~3.5% of participants had mutations that were likely to be clinically relevant.