Top promoted drugs were less likely than top selling and top prescribed drugs to be effective, safe, affordable, novel, and represent genuine advance in treating a disease. Clinicians should question value of drugs most heavily promoted by pharmaceutical manufacturers before prescribing them.

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Top promoted drugs were less likely than top selling and top prescribed drugs to be effective, safe, affordable, novel, and represent genuine advance in treating a disease. Clinicians should question value of drugs most heavily promoted by pharmaceutical manufacturers before prescribing them.