Childhood trauma may affect brain structure, predisposing adults to recurring major depressive disorder. Results suggest that both childhood maltreatment and recurring depression are associated with similar reductions in a part of the brain believed to help regulate emotion and self-awareness.

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Childhood trauma may affect brain structure, predisposing adults to recurring major depressive disorder. Results suggest that both childhood maltreatment and recurring depression are associated with similar reductions in a part of the brain believed to help regulate emotion and self-awareness.