Regular marijuana users need more sedatives during medical procedures. A study of 250 recent patients who had colonoscopies and other procedures found that those who regularly smoked pot or ate edibles needed more fentanyl, midazolam and propofol to be optimally sedated. It’s not totally clear why.

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Regular marijuana users need more sedatives during medical procedures. A study of 250 recent patients who had colonoscopies and other procedures found that those who regularly smoked pot or ate edibles needed more fentanyl, midazolam and propofol to be optimally sedated. It’s not totally clear why.