LSD reduces activity in the amygdala, the region of the brain related to the handling of negative emotions like fear, compared to placebo, in a double-blind, randomised, cross-over study. This may explain it's therapeutic action in addiction, depression and anxiety, especially with psychotherapy.

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LSD reduces activity in the amygdala, the region of the brain related to the handling of negative emotions like fear, compared to placebo, in a double-blind, randomised, cross-over study. This may explain it's therapeutic action in addiction, depression and anxiety, especially with psychotherapy.