The first report of colistin-heteroresistant K. pneumoniae in the United States, that led to colistin treatment (last-line therapy) failure in an in vivo murine model of infection. The data are worrisome, especially since the colistin heteroresistance was not detected by current diagnostic tests.

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The first report of colistin-heteroresistant K. pneumoniae in the United States, that led to colistin treatment (last-line therapy) failure in an in vivo murine model of infection. The data are worrisome, especially since the colistin heteroresistance was not detected by current diagnostic tests.