A study in mice identifies a brain adaptation that underlies the compulsive behavior associated with drug addiction, and which might explain why some drug users behave compulsively whereas others do not. It might explain why some drug users seek reward despite facing negative consequences.

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A study in mice identifies a brain adaptation that underlies the compulsive behavior associated with drug addiction, and which might explain why some drug users behave compulsively whereas others do not. It might explain why some drug users seek reward despite facing negative consequences.