We discovered the first mechanism of how the nucleus shuttles transcription factors from the inner nuclear membrane to DNA to control their activity. This novel paradigm in genomic regulation is exploited by tumors and provides a new battlefield for us to target cancer signaling. (In press at Cell)

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We discovered the first mechanism of how the nucleus shuttles transcription factors from the inner nuclear membrane to DNA to control their activity. This novel paradigm in genomic regulation is exploited by tumors and provides a new battlefield for us to target cancer signaling. (In press at Cell)